“Inhibiting this pathway has extended life span in every species studies to date.”

Anti-aging drug appears to be working

#Health

Sat, Jul 14th, 2018 11:00 by capnasty NEWS

Technology Review reports that drugs which inhibit the aging-related pathway TORC1 has extended the life span in mice and works. The drugs boost the immune system which otherwise is less responsive as people age.

“Immune function was just one of the things that got better,” said Joan Mannick, who worked on the trial at Novartis Institutes for Biomedical Research in Massachusetts. The researchers now have plans to test the drugs on other age-related conditions, such as neurodegenerative diseases.

“This is an extremely important and exciting study,” said Matt Kaeberlein, director of the Healthy Aging and Longevity Research Institute at the University of Washington, who was not involved in the study. The mTOR inhibitors “appear to broadly rejuvenate immune function in healthy elderly people,” he added. “I think this study raises the real possibility that most middle-aged adults could benefit from short-term treatments with mTOR inhibitors.”

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