Region of the Brain That Controls Ageing Discovered


Sun, May 5th, 2013 11:00 by capnasty NEWS

According to Business Week, Scientists at the Albert Einstein School of Medicine have reportedly discovered a region of the brain that "may control aging throughout the entire body. By manipulating that region, they were able to extend the lives of mice by 20 percent."

Mice that were injected with a substance that inhibits NF-κB’s activity lived longer — up to 20 percent longer — while those injected with a substance that stimulated the molecule died earlier.

What’s more, the inhibitor seems to block the lamentable physical decline that occurs with age. Six months after the initial experiment, mice that had been injected with inhibitors performed better than controls on cognition and movement tests. “They also showed less age-related decline in muscle strength, skin thickness, bone mass, and tail-tendon integrity,” according to an article in Nature.

Blocking NF-κB had similar effects on male and female mice and produced anti-aging effects even in middle-aged mice.



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