BBC reports that a French teenager has been free of sickle cell disease for the last 15 months after a world-first procedure involving reprogramming his DNA. While doctors are very careful in calling it a cure, the procedure is still quite an achievement.
Doctors removed his bone marrow - the part of the body that makes blood. They then genetically altered it in a lab to compensate for the defect in his DNA that caused the disease.
Sickle cell is caused by a typo in the instructions for making the protein haemoglobin, which is densely packed into red blood cells.
A virus was used to infect the bone marrow with new, correct instructions.
The corrected bone marrow was then put back into the patient.
|“Salmonella suddenly acquires an insatiable taste for brain tumors.”|
|“If there’s any kind of future for 'designer babies', it might look something like this.”|
|Rants from the waiting room|
|"It’s appealing to imagine a world where artificial wombs grow babies."|
|Walmart Clinic Spotted In The Wild|
|CaptchaTweet: Write Tweets in Captcha Form|
|The (Very Scary) People of Public Transit|
|“The deadlines aren't the problem. It's our failure to heed them.”|
|“The idea of the self-empowered Uber driver or Airbnb host is a rarity if not an outright myth.”|
|Recycled Vacuum Lamps|
|How to Avoid Jury Duty|
|“A mass of meat, ready for human consumption, with no brain or wings or feet.”|
|“Impossible Aerospace founder and CEO Spencer Gore hopes to make self-flying electric planes.”|
|U.S.S. Enterprise Owner's Manual|
|Naked Preacher Lady [NSFW]|
|“World’s largest floatplane-only airline [...] to become an electrically powered airline.”|
|“We are undergoing the greatest economic transformation in our history, and we are dealing with it by pretending nothing is happening.”|