"First successful example of telomere lengthening via gene therapy in a human individual."

Getting biologically younger

#Science

Mon, Apr 25th, 2016 11:00 by capnasty NEWS

According to Neuro Scientist News, Elizabeth Parrish, the CEO of BioViva USA Inc., is the first person to receive experimental gene therapies from her own company that "protect against loss of muscle mass with age" and "battle stem cell depletion" by telomere lengthening.

Telomeres are short segments of DNA which cap the ends of every chromosome, acting as 'buffers' against wear and tear. They shorten with every cell division, eventually getting too short to protect the chromosome, causing the cell to malfunction and the body to age.

In September 2015, telomere data taken from Parrish's white blood cells by SpectraCell's specialized clinical testing laboratory in Houston, Texas, immediately before therapies were administered, revealed that Parrish's telomeres were unusually short for her age, leaving her vulnerable to age-associated diseases earlier in life.

In March 2016, the same tests taken again by SpectraCell revealed that her telomeres had lengthened by approximately 20 years, from 6.71kb to 7.33kb, implying that Parrish's white blood cells (leukocytes) have become biologically younger. [...]

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