By "tricking" cells into thinking they have run out of energy, researchers at Britain's University of Southampton believe that a synthesized molecule dubbed "compound 14" can trigger the same post-exercise events without actually having had a workout.
In the study published in the journal Chemistry and Biology on Monday, scientists gave compound 14 to two different groups of mice. One group was fed a normal diet and the other a high-fat diet which made them obese and impaired their glucose tolerance, an early sign of pre-diabetes.
The results were intriguing: In the normal diet group, blood glucose and weight remained normal. But in the high-fat diet group, a single dose of compound 14 lowered blood glucose to near normal levels. A daily dose for seven days caused them to lose 5 percent of their body weight.
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