On the Duke Medicine website, a look at Stephanie Lipscomb, the first person to receive a modified version of the polio virus used to combat her "aggressive brain cancer." Two years after the procedure the patient is still doing great.
Stephanie was only 20 when she was diagnosed with an aggressive brain tumor called a glioblastoma multiforme. Given only a few months to live, Stephanie underwent surgery to remove the tumor, followed by chemotherapy and radiation. It returned within two years. She agreed to take part in the first phase of a research trial at Duke, during which a modified poliovirus was injected directly into the brain tumor. The investigational approach was pioneered by Matthias Gromeier, MD, an associate professor of neurosurgery and molecular genetics at Duke. He discovered that the poliovirus could kill cancer cells while leaving healthy cells unharmed.
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